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Inicio  Articles SHCA Hips and eyes brochure
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SHCA Hips and eyes brochure |
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[Sólo en inglés]
This brochure is for those who love their Siberian Huskies and are tempted to breed them.
For centuries man has been supervising the breeding of dogs, and exercising his power to choose the
characteristics he wished to preserve and eliminate. This process, known as selective breeding, resulted
in the many individual breeds of dogs that are known today.
Gradually, as breeders became aware of the concepts of genetics, they applied basic genetic principles
to their breeding programs. By combining the art of selection with the knowledge of science, breeders
were able to refine the breeds of their choice.
Much importance has been placed on pedigrees and much success has been derived from the breeding
of closely related dogs that share desirable genetic traits. It was inevitable that, along with the desirable
traits, there have come undesirable traits which may take several generations of breeding to manifest
themselves. When these undesirable traits finally do surface, breeders must acknowledge that their seemingly
normal dogs may transmit defective genes to their offspring and perpetuate the undesirable trait in the breed.
No breed of dog is totally free from inheritable genetic defects, but few breeds have had the good fortune of
the Siberian Husky. Not only is the individual dog generally healthy and of good temperament, but throughout
the years there has not been an abundance of genetic issues. Additionally, the national breed club, the
Siberian Husky Club of America, Inc. (SHCA), has maintained a watchful eye for potential genetic problems
and has taken positive action in those instances when the general health and well-being of the breed has been
challenged.
Since 1965, the SHCA has maintained a committee whose task is to be aware of the start of genetic problems
in the breed and to alert breeders before the defect has begun to spread.
Two major conditions have been uncovered in this manner and, in each instance, the board of directors of
the SHCA has instituted practical guidelines in order to enable breeders to decrease the spread of the inheritable
disorder. These two areas of greatest concern are canine hip dysplasia and inheritable eye disease.
Canine Hip Dysplasia
What is canine hip dysplasia?
Hip dysplasia is an abnormality of the hip joint in which the head of the thighbone (femur) does not
fit properly into its pelvic joint socket (acetabulum). This condition, while not present at birth, develops
during the first two years of the dog's life. It is often progressive, causing inflammation, pain, and
arthritis of the affected hip. It is aggravated by strenuous exercise and, sitting up, lying down, or climbing
stairs.
This disorder afflicts dogs of both sexes, and may be present in one or both hips. The condition may range
from mild to severe, and clinical signs may become more evident in dogs under one year of age. It is
regarded with utmost concern in our breed because the dysplastic Siberian Husky cannot do the work for
which it was bred, nor can it exhibit the freedom and effortlessness of movement so highly prized in the
show ring and on the sled.
What is the cause of hip dysplasia?
Canine hip dysplasia is an inheritable disease. Its mode of inheritance is termed "polygenic," meaning
that it is due to a combination of multiple genes. Because of the polygenic nature of this disorder, some
normal dogs produce a percentage of dysplastic offspring. The breeding pair, although physically normal,
may each transmit some of the dysplastic genes to their offspring, thus the offspring may receive a
combination of complementary genes from both parents which may cause hip dysplasia. The division of
defective genes is very uneven, with one parent contributing more defective genes than the other.
Environmental factors such as a high caloric diet during the rapid growth phase of a puppy can exacerbate
the changes in dysplastic hips, but cannot create a dysplastic dog.
How is hip dysplasia diagnosed?
Accurate diagnosis can be established through radiographic examination by a veterinary radiologist.
The dog is sedated and the hind limbs are rotated and extended to allow the proper positioning of the
hips and femurs. It is recommended that bitches in heat or in pregnancy not be radiographed since
the hormones may interfere with joint laxity. After the films are taken, they are mailed to a hip registry
organization such as the OFA or Penn Hip. Since the OFA has been the most commonly used hip registry
in the world, only the OFA will be discussed.
What is OFA?
The Orthopedic Foundation for Animals (OFA) is a private, non-profit organization which disseminates
information on orthopedic and genetic diseases to the public. It is the world's largest all-breed hip
registry, with over 475,000 dogs. After a veterinarian takes an x-ray of the dog's hips, the x-ray is mailed
to OFA for hip evaluation. The radiograph is then evaluated independently by three board certified
veterinary radiologists. The final hip grade is decided by a consensus of the three independent radiologists.
Only dogs over 24 months of age that receive "excellent," "good," or "fair" evaluations will receive an
OFA registry number. This number is reported to the AKC and parent breed club. Abnormal hips are only
reported to the owner and referring veterinarian. Dogs under 24 months of age can have a preliminary hip
evaluation, but a registry number will not be assigned until new radiographs have been resubmitted at 24
months of age.
How common is canine hip dysplasia in the Siberian Husky?
From January 1994 through December 1998, a total of 12,087 Siberian Huskies have been evaluated by OFA
for hip dysplasia. Out of this total, 30.5% of the dogs have received "excellent" hip ratings, and only 2.2%
have been dysplastic. (Please note that radiographs showing hip dysplasia may not have been mailed to the
OFA on the advice of the referring veterinarian.)
Out of the 114 breeds of dogs at risk for hip dysplasia, the Siberian Husky is one of the breeds least affected
ranked at #111 out of a possible 114 based upon evaluations from 1974 through 1994. This impressive
ranking has been achieved through the cooperation of
breeders who followed the breeding program guidelines established by the OFA and the SHCA to decrease
the incidence of hip dysplasia.
The Siberian Husky has been one of the few breeds that had a dramatic decrease in the incidence of hip
dysplasia from 1980 through 1995. The breed has experienced a change of + 42.1% in the number of OFA
"excellent" dogs, and a - 55.6% change in the number of dysplastic dogs.
All potential puppy buyers should ask to see the OFA registry papers of both the sire and dam of the litter.
How can I find out if a dog has an OFA number?
The OFA maintains a hip registry open to the public and is available on the OFA website at the following
address: http://www.offa.org
The person to contact for OFA information is:
Alice Watt, SHCA OFA/SHOR Chairperson
6922 Fruitland Road
Salem, Oregon 97301
What are the guidelines for preventing dysplasia?
Only those dogs which have been certified free from hip dysplasia by the OFA should be used for breeding.
Whenever possible, close relatives to dysplastic dogs should not be used for breeding even if they are
physically normal. Vital to the program is the establishment of "pedigree depth" for each individual stud
dog or brood bitch. In order to establish pedigree depth, the parents, grandparents, and all close relatives
of the stud dog or brood bitch should also be certified by the OFA. Many breeders have already adhered
to this protocol and have had an admirable record of dysplasia-free stock for generations of dogs.
Genetic Defects of the Eye
Which inherited eye defects occur in the Siberian Husky?
Although there are many possible eye defects, only three are of current concern in the Siberian.
These are hereditary or juvenile cataracts, corneal dystrophy, and progressive retinal atrophy.
Each disorder is present in a different portion of the eye, and will occur in any eye color. Eye defects
in the Siberian Husky are serious and should not be understated or overlooked.
What are hereditary cataracts & how are they transmitted?
Hereditary or juvenile cataracts are manifested by opacity in the lens of a young dog as early as 3 months
of age. These cataracts are different from the non-hereditary cataracts affecting aged or senior dogs. The
function of the lens of the eye is to focus the rays of light so that they form an image on the retina. An opacity
or cataract on the lens causes less light to enter the eye and sight can be diminished. A cataract can cause a
mild decrease in eyesight to complete blindness in severe cases. Cataracts can further be classified by location
and stage of development. The most common hereditary cataract in the Siberian Husky occurs on the
posterior region of the lens. It is not uncommon for a cataract to develop in one eye months before the other
eye shows the effects of the disease. Recent DNA research indicates that juvenile cataracts may be carried by
a recessive gene. Genetic research is presently under way to develop a simple DNA test to identify dogs and
bitches that carry the recessive gene for cataracts.
What is corneal dystrophy?
Corneal dystrophy affects the cornea or the outer transparent portion of the eyeball. In most cases, Siberian
Huskies with this disorder have an abnormal collection of lipids in the clear cornea of the eye which results
in a hazy or crystalline opacity. Ophthalmologists describe the location of the opacity as anterior, mid, or
deep stromal. The Siberian Husky is prone to deep stromal dystrophy which involves triglyceride deposits.
Annular dystrophy also occurs and appears as a doughnut shaped opacity in the peripheral cornea. Corneal
dystrophy is usually seen in young adult dogs and may affect females more than males. Vision is seldom
affected and no effective therapy for the condition exists at this time. Recent genetic tests are suggesting
that a recessive gene with variant expression transmits this disorder.
What is progressive retinal atrophy (PRA) & how is it transmitted?
Progressive retinal atrophy (PRA) affects the retina, the light-sensitive inner lining of the posterior part of
the eyeball. The retina contains two types of specialized cells called rods and cones. The rods are necessary
for sight in dim light or night light, and the cones are utilized in in bright light vision. The Siberian Husky
has a unique type of PRA that is only found in Siberians and man. This type of PRA is called XLPRA (X
Linked PRA) since it is transmitted through the "XX" chromosome of the female. It will cause a loss of night
vision followed by a loss of day vision, eventually blindness. The recessive gene for XLPRA is situated on the
"X" chromosome of the female. Females who inherit a defective gene on the "X" chromosome from one parent
and a normal gene on the other "X" chromosome from the other parent, will not be seriously affected. They
will be carriers with very subtle retinal defects and no loss of vision. The male puppy from a carrier dam will
receive either a defective gene or a normal gene, depending on what chromosome was copied in the DNA
replication. If he has the defective gene, the dog will be affected with PRA since males carry an "XY"
chromosome. The disease in males can be devastating with loss of vision as early as 5 months of age.
A genetic test is being developed to identify carrier females in the Siberian Husky. Once this test is available,
XLPRA can be eliminated from breeding programs.
How are eye defects diagnosed?
Accurate diagnosis of eye defects requires the expertise of a board certified veterinary ophthalmologist
who is equipped by knowledge and training to distinguish hereditary eye diseases from non-hereditary
eye disorders. The American College of Veterinary Ophthalmologists (ACVO)is the national governing
board for the certification of veterinary ophthalmologists. Since 1974, the SHCA has encouraged local breed
clubs to support eye clinics, which make eye examination more convenient and affordable to breeders and
dog owners. Today, thanks to the devotion and support of local area clubs, eye clinics are common
throughout the country and are available to all breeders.
How prevalent are eye defects in the Siberian Husky?
Of the three major eye diseases of the Siberian Husky, hereditary cataracts are the most common, followed
by corneal dystrophy, and progressive retinal atrophy. A statistical report conducted by members of the
American College of Veterinary Ophthalmologists in 1999 provided the following information regarding the
Siberian Husky. Out of 1345 Siberian Huskies examined, a total of 107 dogs had inheritable cataracts (8%), a
total of 44 dogs had corneal dystrophy (3%), and 4 dogs had progressive retinal atrophy (less than 1%).
How can genetic eye defects be reduced or eliminated?
Research is now being conducted to develop DNA testing for both hereditary cataracts and progressive
retinal atrophy. Until these tests are available, the SHCA and the American College of Veterinary
Ophthalmologists have established guidelines to help breeders decrease the spread of heritable eye
disorders. The guidelines are as follows: Every dog to be used for breeding must be examined by a
veterinarian that is board certified by the American College of Veterinary Ophthalmology. This examination
must be done during the year that the dog is to be used for breeding. Only dogs with normal examinations
are to be used for breeding. Caution must be exercised in the use of those dogs that are closely related to
affected dogs, or when a breeder suspects that an individual dog is producing a defect in its offspring. Though
the dog itself may not exhibit signs of the eye defect, that dog should promptly and permanently be withheld
from further breeding.
Is there a breed registry available for normal eyes?
Since eye abnormalities can appear over a period of several years, annual eye examinations are imperative.
It is possible for a dog to have a normal eye examination at one year of age and be severely afflicted with an
eye disorder one or two years later. In the case of hereditary eye disease, consideration must be given to the
possibility that the defect occurs as a genetic recessive gene. In this instance, two normal dogs that are
carriers of the defect will pass the eye exam and yet pass the genetic defect to the offspring.
In 1975, a central agency was formed to register annual eye examination reports for all breeds. The agency,
named the Canine Eye Registry Foundation (CERF), compiled eye data and reports for all breeds. In
addition, upon receipt of an approved eye examination form signed by an ACVO veterinary ophthalmologist,
the registry issued adult dog certificates and breed numbers which included the date of the eye examination
along with the current age of the dog. The certificate was good for one year.
When CERF disbanded in 1979, the SHCA instituted the Siberian Husky Ophthalmologic Registry (SHOR).
This agency continued the function of registering Siberian Huskies that had completed an ACVO annual
eye examination. In order to receive a SHOR certification, which is only valid for one year, the dog has to
be at least one year of age. The SHOR registry number consists of three segments:
1. an individual number sequential to the number of previously certified dogs;
2. the month and year of the examination;
3. the age in months of the dog at the examination.
The name of the dog and the registry number are published in the Newsletter of the SHCA.
In 1982 the CERF eye registry was reinstituted and at present, both the CERF and SHOR registries are
available for eye certification.
Reputable breeders of Siberian Huskies provide current eye examination reports by ACVO veterinary
ophthalmologists for all breeding stock. All potential puppy buyers should ask to see the eye examination
report for both the sire and the dam of the litter.
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